Gavin Wright

1)    Vaccine target identification for neglected tropical infectious disease including  visceral leishmaniasis (L. donovani), animal African trypanosomiasis (T. vivax and T. congolense) and malaria (P. falciparum). We have large panels of recombinant cell surface and secreted proteins from these pathogens and also murine infection models set up for L. donovani, T. vivax, and T. congolense.
2)    Host-pathogen interactions. We have developed systematic genome-scale platforms to identify host receptors for parasite ligands.
3)    Diagnostics: we can use our panels of proteins to identify markers of exposure.